MiRNAs are believed to be promising biomarkers for the diagnosis and prognosis of viral infections. The hypothesis of this study is that the profile of miRNAs in plasma and respiratory secretions for patients with severe COVID-19 infection will be different from patients with non-severe infection.
This study will help identify one or more specific miRNA biomarkers for severe COVID-19 infection. This will make it possible to assess the prognosis of patients and identify cell marking pathways involved and thus potentially identify new targets for treatment.
Identification of differentially expressed miRNAs between patients with severe COVID-19 infection and those with non-severe infection
Secondary objective: to discover miRNAs that could play a role in the pathophysiology of the COVID-19 infection.