RESULTS

Since the beginning of the epidemic, the Lille Task Force institutions have been involved in a very large number of therapeutic and observational research projects.

In just a few weeks, it was possible to publish the initial results found in Lille, with a major impact on the understanding of the virus and the epidemic:

  • On 9 April 2020, an article published in “Obesity” shows that patients suffering from obesity are seven times more likely to be placed on a ventilator than patients with a regular weight.
  • On 23 April 2020, an article published in “Intensive Care Medicine” on histological lung analyses shows that pneumonia due to COVID-19 is not linked to alveolar exudate like in most cases of respiratory distress in intensive care but that it is characterized by intra-alveolar fibrin deposits, opening up prospects for the use of anti-inflammatory drugs.
  • On 24 April 2020, an article published in “Circulation” shows the high prevalence of pulmonary embolism cases, which increased more than twofold, among patients hospitalized for Covid-19.

To consolidate these initial preliminary results, the task force is coordinating and supporting 28 research projects on Covid-19. The results will be published in this section.

Prone positioning under VV-ECMO improves oxygenation in SARS-CoV-2-induced ARDS without compromising the safety of the patients.
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